b'COVID-19s Spike Protein Interacting with ACE2 Receptor When Bound to Human Serum GlobulinShawn Anderson, Anna Beth Boyette, Sarah Kate Boyette, Ja Kierra Foston, Nathan Hart, Kayla Mills, Chloe Ward, and Cleanthi G ZuppasSponsor: Dr. Thomas ManningUsing computational techniques, QSAR, we developed a novel method to treat and cure COVID-19 patients. Understanding QSAR (Quantitative Structure Activity Relationship) is essential for chemistry and pharmaceuticals based on the idea that when we change the structure of a molecule, the function of that molecule also changes. The ACE2 enzyme acts as an entry point for the coronavirus to enter the cell using its spike protein. The Segment of coronavirus spike protein attached the ACE2 receptor blocks COVID from receptor. The common serum protein globulin is used to transport the spike protein peptide to the lungs. Binding the drug results in an occupied ACE2 site, preventing the coronavirus from entering the cell and later using the cell to disperse many virus particles into the rest of the body.Inhalation Studies Using an electronic Vaporization Involving a Novel Cancer DrugKayla Mills, Khyati Patel and James Nienow Sponsors: Dr. Thomas Manning, VSU Department of Chemistry Dr. Dennis Phillips, UGaMass Spec Lab and Dr. Greg Wylie, Texas A&M NMR LabAn iron-copper medical complex was developed at VSU as a new type of cancer drug. It is based on using the metals, which cancer cells use in higher quantities compared to healthy cells, as a method to accelerate the uptake of the drug in the cancer cell. This complex was accepted into the National Cancer Institute 60 cell line panel for in vitro testing against nine types of cancer. It progressed through 3 levels of evaluation. This poster will outline some experiments that are aimed at evaluating if the complex can be administrated by electronic vaporization as a method to treat lung cancer or leukemia. The electronic technique involves rapidly heating the sample that is dissolved in an alcohol to form nanodroplets, which are needed to penetrate deep within a patients lungs. The ability to permeate lung alveoli and enter serum is critical for treating leukemia.18'