b'A Structure Validation Tool for Cryo-EM Proteins in ChimeraX PlatformStefan C. Atkinson and Kevin J. EppesSponsors: Dr. Lin Chen and Dr. Anurag Dasgupta, Department of Computer ScienceCryo-electron microscopy (cryo-EM) has become a significant technique for protein structure determination. The deposition of cryo-EM proteins into the Worldwide Protein Data Bank (wwPDB) has increased steadily from 11 in 2000 to 1423 in 2019. However, we note that there are plenty of suspicious defects in proteins solved from cryo-EM in the Protein Data Bank (PDB). These potential structural errors might be due to the lack of features for cryo-EM proteins in the current validation pipeline at wwPDB. We designed a validation tool, with several unsupervised machine learning models built in, to identify the defects. A Graphic User Interface (GUI) for ChimeraX protein visual platform was designed to help structural biologists identify reasons for introducing conformation defects in the protein modeling process.HistoryThe Siege of Alesia: Caesar as a Military LeaderBryan Cordell MoatsSponsor: Dr. John Dunn, Department of HistoryThis research sheds light on an important event in the life of Julius Caesar, one of the best-known figures from the ancient world. Before Caesar became the famous figure he is in modern society, he learned his leadership skills while leading the military through the Gallic Wars. The Siege of Alesia is a great example of how Caesar led his military, from personally fighting on the front lines, to developing unique and effective ways to turn the tide of battle to his favor. This research on the Gallic Wars is an aspect of Caesars life that has not been explored as often as the rest of his career, such as the later Civil Wars and Caesars time ruling over Rome.His ultimate victory at Alesia established his military and political capital that allowed Caesar to subsequently become the master of Rome.48'